Publications

See the complete list of Dr. Dutta’s published work

Selected Publications:

Vasamsetti SB, Florentin J, Coppin E, Stiekema L, Zheng KH, Nisar MU, Levinthal D, Rojas M, Stroes ES, Kim K, Dutta P. Sympathetic neuronal activation triggers myeloid progenitor proliferation and differentiation. Immunity. 2018. pii: S1074-7613(18)30240-1. doi: 10.1016/j.immuni.2018.05.004.  PMID: 29958804.

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Florentin J, Coppin E, Vasamsetti SB, Zhao J, Tai YY, Tang Y, Zhang Y, Watson A, Sembrat J, Rojas M, Vargas SO, Chan SY*, Dutta P*. Inflammatory macrophage expansion in pulmonary hypertension depends upon mobilization of blood-borne monocytes. J of Immunol. 2018. (Epub ahead of print). PMID: 29632145. *Co-senior authors.

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Coppin E, Florentin J, Vasamsetti SB, Arunkumar A, Sembrat J, Rojas M, Dutta P. Splenic hematopoietic stem cells display a pre-activated phenotype. Immunol Cell Biol. 2018 (Epub ahead of print). IMID: 29526053

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Dutta P, Hoyer FF, Sun Y, Iwamoto Y, Tricot B, Weissleder R, Magnani JL, Swirski FK, Nahrendorf M. E-selectin inhibition mitigates splenic HSC activation and myelopoiesis in hypercholesterolemic mice with myocardial infarction. Atheroscler Thromb Vasc Biol 2016 Sep;36(9):1802-8. PMCID: PMC5001901

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Bracamonte-Baran W, Florentin J, Zhou Y, Jankowska-Gan E, Haynes WJ, Zhong W, Brennan TV, Dutta P, Class FH, va Rood JJ, Burlingham WJ. Modification of host dendritic cells by microchimerism-derived extracellular vesicles generates split tolerance. Proc Natl Acad Sci Jan 31;114(5):1099-1104. PMCID: PMC5293109

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Sager HB*, Dutta P*, Dahlman JE, Borodovsky A, Fitzgerald K, Heidt T, Courties G, Wojtkiewicz GR, Iwamoto Y, Sebas M, Khan OF, Xing Y, Shaw TE, Libby P, Swirski FK, Langer R, Weissleder R, Anderson DG, Nahrendorf RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction. Sci Transl Med. 2016 Jun 8;8(342):342ra80 PMID: 27280687. *Equal contribution

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Dutta P, Sager H, Stengel K, Naxerova K,……Libby P, Hiebert S, Scadden D, Swirski FK, Weissleder R, Nahrendorf M. 2015. Myocardial infarction activates CCR2+ hematopoietic stem cells. Cell Stem Cell 16: 477-87.
Correspondence: Partha Dutta (dutta.partha@mgh.harvard.edu) and Matthias Nahrendorf (mnahrendorf@mgh.harvard.edu)

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Dutta, P., F. F. Hoyer, L. S. Grigoryeva, H. B. Sager, F. Leuschner, G. Courties, A. Borodovsky, T. Novobrantseva, V. M. Ruda, K. Fitzgerald, Y. Iwamoto, G. Wojtkiewicz, Y. Sun, N. Da Silva, P. Libby, D. G. Anderson, F. K. Swirski, R. Weissleder, and M. Nahrendorf. 2015. Macrophages retain hematopoietic stem cells in the spleen via VCAM-1 in atherosclerosis. Journal of Experimental Medicine 212: 497-512.
Correspondence: Partha Dutta (dutta.partha@mgh.harvard.edu) and Matthias Nahrendorf (mnahrendorf@mgh.harvard.edu)

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Sager HB, T. Heidt, M. Hulsmans, Dutta, G. Courties, M. Sebas, G. R. Wojtkiesicz, B. Tricot, Y. Iwamoto, Y. Sun, R. Weissleder, P. Libby, F.K. Swirski, M. Nahrendorf. 2015. Targeting interleukin-1beta reduces leukocyte production after acute myocardial infarction. Circulation.

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Dutta, P., G. Courties, Y. Wei, F. Leuschner, R. Gorbatov, C. S. Robbins, Y. Iwamoto, B. Thompson, A. L. Carlson, T. Heidt, M. D. Majmudar, F. Lasitschka, M. Etzrodt, P. Waterman, M. T. Waring, A. T. Chicoine, A. M. van der Laan, H. W. Niessen, J. J. Piek, B. B. Rubin, J. Butany, J. R. Stone, H. A. Katus, S. A. Murphy, D. A. Morrow, M. S. Sabatine, C. Vinegoni, M. A. Moskowitz, M. J. Pittet, P. Libby, C. P. Lin, F. K. Swirski, R. Weissleder, and M. Nahrendorf. 2012. Myocardial infarction accelerates atherosclerosis. Nature 487: 325-329.

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Heidt, T., H. B. Sager, G. Courties, Dutta, Y. Iwamoto, A. Zaltsman, C. von Zur Muhlen, C. Bode, G. L. Fricchione, J. Denninger, C. P. Lin, C. Vinegoni, P. Libby, F. K. Swirski, R. Weissleder, and M. Nahrendorf. 2014. Chronic variable stress activates hematopoietic stem cells. Nature Medicine 20: 754-758.

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Leuschner, F*., Dutta*, R. Gorbatov, T. I. Novobrantseva, J. S. Donahoe, G. Courties, K. M. Lee, J. I. Kim, J. F. Markmann, B. Marinelli, P. Panizzi, W. W. Lee, Y. Iwamoto, S. Milstein, H. Epstein-Barash, W. Cantley, J. Wong, V. Cortez-Retamozo, A. Newton, K. Love, P. Libby, M. J. Pittet, F. K. Swirski, V. Koteliansky, R. Langer, R. Weissleder, D. G. Anderson, and M. Nahrendorf. 2011. Therapeutic siRNA silencing in inflammatory monocytes in mice. Nature Biotechnology 29: 1005-1010. * Equal contribution authors

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Dutta, P., M. Dart, D. A. Roenneburg, J. R. Torrealba, and W. J. Burlingham. 2011. Pretransplant immune-regulation predicts allograft tolerance. Am J Transplant 11: 1296-1301.

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Dutta, P., M. Molitor-Dart, J. L. Bobadilla, D. A. Roenneburg, Z. Yan, J. R. Torrealba, and W. J. Burlingham. 2009. Microchimerism is strongly correlated with tolerance to noninherited maternal antigens in mice. Blood 114: 3578-3587.